Storage:
active substance: pancreatin;
1 gastro-resistant tablet contains pancreatin with an enzymatic activity of at least 10,000 lipolytic units of Ph. Eur., 7,500 amylolytic units Ph. Eur., 400 proteolytic units Ph. Eur.;
excipients: sodium chloride, colloidal anhydrous silicon dioxide, microcrystalline cellulose, crospovidone, croscarmellose sodium, povidone 25, magnesium stearate, methacrylate copolymer dispersion, talc, propylene glycol, titanium dioxide (E 171), carmoisine (E 122).
Pharmaceutical form. Tablets are gastroresistant.
The main physicochemical properties: tablets of a round shape, covered with a shell, with the upper and lower convex surfaces, pink in color, with a weak specific smell. A core surrounded by one solid layer can be seen on the crack under a magnifying glass.
Pharmacotherapeutic group.
Agents affecting the digestive system and metabolism. Digestive aids, including enzymes. Polyenzyme preparations (lipase, protease, etc.).
Clinical characteristics.
Indication.
Diseases that are accompanied by a violation of the process of digestion of food due to insufficient secretion of digestive enzymes by the pancreas, such as chronic pancreatitis.
Conditions after simultaneous resection of the stomach and small intestine, functional acceleration of the passage of food through the intestine, intestinal disorders, simultaneous consumption of hard-to-digest vegetable, fatty and unusual food.
Intestinal bloating.
Preparation for x-ray or ultrasound diagnostic studies.
Contraindication.
Increased sensitivity to the active substance and other components of the medicinal product. Acute pancreatitis, exacerbation of chronic pancreatitis, intestinal obstruction.
Method of application and dosage.
The dose of the drug depends on the deficiency of pancreatic enzymes in the duodenum and is set individually.
If there are no other recommendations, as well as in case of consumption of hard-to-digest vegetable food, fatty or unusual food, take 1-2 tablets. In other cases mentioned above, when digestive disorders occur, the recommended dose is 2-4 tablets. If necessary, the dose of the drug can be increased. Increasing the dose in order to reduce symptoms of the disease, such as steatorrhea or abdominal pain, should be carried out only under the supervision of a doctor. The daily dose of lipase should not exceed 15,000 – 20,000 U Ph. Eur. per 1 kg of body weight.
Tablets should be taken with a meal, swallowing whole and with a large amount of liquid, for example, 1 glass of water.
The duration of treatment depends on the course of the disease and is determined by the doctor individually.
Children.
There is no experience of using the drug in children, so it is not recommended to prescribe it to this age category of patients.
Overdose.
Symptoms Side effects may increase. Hyperuricemia and hyperuricosuria have been observed when taking extremely high doses of other pancreatic powder preparations.
Treatment. Drug discontinuation, adequate hydration, and symptomatic therapy
Storage conditions.
Store in the original packaging at a temperature not higher than 25 ºС.
Keep out of the reach of children.
Packaging.
10 tablets in a blister. 1 or 2 or 5 blisters in a cardboard pack.
Leave category.
Without a prescription.
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